Odactra vs. Allergy Shots vs. Allergy Drops is an important question for patients with dust mite allergic rhinitis. Therapy can consist of oral antihistamines, nasal antihistamines and nasal steroids to manage the symptoms of allergic rhinitis.
Although medications are effective, 62% of adults and 29% of children experience partial or poor relief of symptoms through pharmacotherapy. In cases like this. allergy immunotherapy should be considered.
The most common forms of allergen immunotherapy come in 2 forms.
- Subcutaneous Immunotherapy (SCIT) also known as allergy shots.
- Sublingual Immunotherapy (SLIT) also known as allergy drops or allergy tablets
SCIT is considered the conventional modality and is highly effective. However it can be time consuming and there can be adverse reactions. A recent study evaluated the efficacy of Odactra (which are house dust mite tablets) vs. Allergy Shots vs. SLIT (using allergy drops).
Results: 26 double blind clinical trials were included in this study. In all immunotherapy studies, a significant reduction of the symptoms was observed compared to placebos. For the medication score, a significant reduction was seen for allergy 3 treatment modalities.
Overall, the clinical efficacy of SCIT (Allergy Shots) was greater than for SLIT drop or SLIT tablets. SCIT showed greater efficacy for nasal and/or eye symptoms.
Taken all the studies together for allergy immunotherapy for house dust mite allergies, the therapeutic effect of SCIT in controlling allergic rhinitis was greater than those of SLIT drop or SLIT tablet (Odactra). The clinical efficacy of SLIT drop and SLIT tablet was comparable.
Allergy shots have been around a lot longer than sublingual tablets and drops. Based on this study “Efficacy of Subcutaneous and Sublingual Immunotherapy for House Dust Mite Allergy: A Network Meta-Analysis-Based Comparison”, all forms of immunotherapy are helpful in reducing allergic rhinitis symptoms. But overall when you compare Odactra vs. Allergy Shots vs. Allergy Drops, the efficacy of the shots seems to work best.