Multiple epinephrine dosages are sometimes need for anaphylaxis. Anaphylaxis is a severe, potentially fatal allergic reaction. Intramuscular epinephrine is the recommended treatment in the the setting of anaphylaxis and the current recommendation is for patients to carry 2 doses of self-injectable epinephrine. Previous studies have evaluated food-induced allergic reactions that require multiple epinephrine injections in […]
NBA Rookie Zhaire Smith’s Allergic Reaction
In reported news today, Zhaire Smith of the Philadelphia 76’ers will be out possibly the whole NBA 2018-2019 season due to complications from an allergic reaction. It was known that the rookie had a peanut allergy and food was individually prepared for him at the teams facility so he was not exposed to peanut. Apparently […]
Primatene Mist OTC gets FDA Approval
Primatene Mist OTC is making a comeback as it was recently FDA approved. Primatene Mist was taken off the market in the past because it contained CFC propellants that destroyed the ozone layer, we discussed this several years ago. Primatene Mist not likely to get FDA approval But the new version of Primatene Mist OTC […]
Alternaria mold is associated with Asthma
The importance of Alternaria mold exposure to allergic disease is underrecognized in urban communities compared to dust mites, cockroach and mouse exposure. Concentrations of Alternaria mold are higher in outdoor than in indoor air, however dampness, leaks can cause fungal penetration and growth indoors. Given the amount of time people spend indoors, indoor exposure may […]
Pectin Allergy, a potential hidden food allergen
Pectin allergy is not very common, but it can be a source of allergy for patients sensitive to cashew and pistachio. Food allergy is estimated to affect 6-8% of children in the United states and it is associated with a risk of anaphylaxis. Despite avoidance to culprit foods, hidden allergens can be a source of […]
Statins for Asthma, do they help?
Statins for asthma have been recently looked at as they have anti-inflammatory and immunomodulatory effects. Asthma is a respiratory syndrome defined by reversible airway obstruction and increased hyperreactivity of the airways. The estimated prevalence in some studies show asthma prevalence up to 13% worldwide. Statins are prescribed for elevated cholesterol and prevention of cardiovascular disease. […]
Are Two EpiPens Really Necessary?
Having two epipens has become more difficult for patients due to recent shortages, rising prices and manufacturing difficulties. Anaphylaxis is a life-threatening allergic reaction characterized by skin, respiratory and gastrointestinal allergy symptoms with a rapid onset. Anaphylaxis affects both adults and children and it can occur up to 2% of the population. Among pediatrics, the […]
Tralokinumab for Asthma
Tralokinumab is an IL-13 neutralizing monoclonal antibody being investigated for severe asthma. The success of neutralization of IL-5 for the treatment of severe eosinophilic asthma has increased investigation into the therapeutic potential of other type 2 cytokines, including IL-13. 3 recent trials have been conducted to assess the efficacy of tralokinumab, an IL-13 neutralizing mAb, […]
Accidental Food Allergy Reactions
Accidental food allergy reactions to food are frequent and can be severe and even fatal. Food allergy is a serious health problem affecting 1-3% of the population. For many patients with food allergy, these allergies are best managed by avoidance of the allergenic food. Legislation on food labeling is implemented in most regions of the […]
Inhaled Triple Therapy for Respiratory Disease
Inhaled triple therapy is being recommended for patients with severe chronic obstructive pulmonary disease (COPD) as a step up therapy. Inhaled triple therapy consists of 3 ingredients; Inhaled corticosteroids Long acting muscarinic antagonists (LAMA) Long acting Beta agonists (LABAs) This is considered a step up therapy for patients with frequent exacerbations. Two recent studies were […]
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