Eohilia, a budesonide oral suspension is set to be the first FDA approved treatment for eosninophilic esophagitis. Takeda pharmaceuticals is the manufacturer of the drug. Eosinophilic esophagitis (EoE) is a chronic, immune-mediated, inflammatory disease localized in the esophagus. The prevalence of EoE is rising. Approximately 1 in 2000 people in the US live with EoE. […]
Indacaterol for severe asthma
Indacaterol is an ultra long acting beta agonist that is currently only FDA approved to treat COPD. Indacaterol containing inhalers have shown promise in 2 recent phase 3 trials in patients with severe uncontrolled asthma. For both trials, the endpoint was measured on spirometry and it studied the FEV1 after 26 weeks of treatment. In […]
New treatments for chronic hives
New treatments for chronic hives are currently being studied. Chronic urticaria or hives is defined as having urticaria for more than 6 weeks duration. Chronic hives have been called chronic idiopathic urticaria, chronic autoimmune urticaria or chronic spontaneous urticaria. There is also chronic inducible urticaria which can be brought on by cold, delayed pressure, solar, […]
Xolair for Allergic Rhinitis-A recent study
Xolair for allergic rhinitis may become a future treatment option for patients. Currently Xolair which is an anti-IgE antibody is indicated for moderate to severe persistent asthma and chronic idiopathic urticaria. But the mechanism of action lends itself to treating allergic rhinitis. Allergic rhinitis is one of the most common and increasing diseases worldwide, affecting […]
Semen allergy an overview and treatment
Semen allergy or seminal plasma hypersensitivity (SPH) presents with a localized vaginal and/or systemic allergic symptoms on exposure to its protein components. Although the true incidence is unclear, its is likely underdiagnosed but an important cause of vaginal swelling and pain during/after intercourse. Systemic allergic reactions can happen that may even require the use of […]
Peanut Patch (Viaskin) for peanut allergy
A peanut patch is being developed by DBV Technologies for peanut allergy. Peanut allergy affects up to 2.2% of the children in the United States, equating up to 1.6 million children. Those with peanut allergy report the highest rates of anaphylaxis and severe reactions. Peanut allergy children have more ER visits compared to other children […]
Ara h 2 is the most important peanut allergen
Peanut allergy is a prominent IgE-mediated food allergy that can cause anaphylaxis and it is increasing in prevalence. Peanut allergy appears to be particularly persistent. Detection of allergen specific IgE supports the diagnosis of peanut allergy. Peanut Component Testing, can help diagnose specific peanut allergy. There are over 13 allergenic components identified in peanuts. The […]
Xolair for Nasal Polyps
The treatment of Xolair for nasal polpys is currently being investigated. Chronic sinusitis with nasal polyps is common and is estimated to affect up to 15% of the population. It is associated with adult onset asthma. Many patients have uncontrolled symptoms despite use of nasal steroids. Even after surgery up to 80% of patients can […]
Grayson Dolan from the Dolan Twins visits Dr. Khadavi
Grayson Dolan from the Dolan Twins pays a visit to Dr. Alan Khadavi. He is interested in getting a dog or cat and he wants to see what he is allergic to. Below is the YouTube link to his episode, he enters Dr. Khadavi’s office at the 9:15 mark. Grayson got wifed up already? Another […]
Season of birth and allergies
A recent study showed that the relationship of season of birth and allergies. Notably, food allergy and atopic dermatitis (eczema) are more common on among children born during the fall season. Previous studies have shown this relationship in Asia and Europe with mixed results. “The effect of season of birth on atopic dermatitis and food […]