With so many options available, the best nasal polyps treatment can be hard to pick. Chronic rhinosinusitis with nasal polyps is an inflammatory disease of the upper airways characterized by polyp growth in the nasal passages. It causes severe congestion, discharge and difficulty with smell. The best treatment option is unclear. A study published in […]
Fasenra for Nasal Polyps, a new treatment option
Fasenra for nasal polyps is currently being studied as a future therapeutic option. Chronic sinusitis with nasal polyps is an inflammatory condition associated with symptoms that may be severe, including rhinorrhea, nasal blockage and congestion, loss of smell, facial pressure/pain. Nasal sprays have shown limited help and surgery only helps temporarily as many of them […]
Asivatrep a new topical treatment for Eczema
Asivatrep is a new potential treatment for eczema (atopic dermatitis). Atopic dermatitis is a chronic inflammatory itchy skin disease that affects up to 25% of children and 10% of adults. The cause is complex and multifactorial. Currently there are few classes of topical medications to treat it. Steroids Calcineurin inhibitors (Elidel, Protopic) Phosphodiesterase 4 inhibitors Eucrisa […]
Kiwi Allergy can come in many flavors
Kiwi allergy is not commonly reported, but it can cause adverse reactions. Hypersensitivity reactions to other fruits are commonly reported, particularly fruits in the birch tree family: apple, hazelnut, carrot and potato, these may be symptoms of oral allergy syndrome. Kiwi is also known as a Chinese gooseberry. Kiwi has a slightly acidic flavor that […]
Ana o 3 IgE in diagnosing Cashew Nut Allergy
Cashew nut allergy is on the rise, Ana o 3 IgE seems to be the best single test to diagnose cashew allergy. Cashew nut belongs to the Anacardiaceae family, along with pistachio nut and mango. Cashew and pistachio nut cross-react both in IgE testing and clinically. Cashew nut is typically consumed as a snack and […]
Does Expired Albuterol work?
Does expired albuterol work? Expiration dates of pharmaceutical products are important to know. They are based on stability studies conducted by manufacturers. Expiration dates imply that the medications no longer retain their potency and should be discarded once its reached, but in facts, the post expiration residual drug strength is usually undetermined. In fact in […]
Itepekimab in Asthma and COPD
Itepekimab is an anti-Il-33 monoclonal. Il-33 is an epithelium-derived cytokine that promotes Th2 immune responses in response to cellular damage with roles in asthma and COPD (Chronic Obstructive Pulmonary Disease). Two randomized controlled clinical trials were performed assessing the efficacy of Itepekimab in asthma and COPD. After identifying the asthma associated variants in the genes […]
Dr. Alan Khadavi’s Food Allergy Podcast Talk
Dr. Alan Khadavi was recently featured on the food allergy podcast with Lisa Horne. Topics covered were: Signs and symptoms of food allergy Signs and symptoms of new additional food allergies Different ways food allergy presents (hives and some “atypical” presentations vs other less obvious presentations) What method to go through pediatrician and primary care […]
Can you eat sesame seeds if you are allergic to sesame?
Sesame allergy has gained popularity in the Western diet, it is mainly consumed as intact sesame seeds in baked products. Sesame allergy has a prevalence in the U.S. of about 0.2% and in Israel where it is more widely consumed of 0.93%. In Israel, sesame is a major cause of IgE-mediated food allergy. Sesame allergy […]
Xolair, Dupixent or Nucala for Nasal Polyps?
Xolair, Dupixent and Nucala all have the indication to treat chronic rhinosinusitis with nasal polyps. Conventional treatment involves nasal surgery (debulking polypectomy and sinus surgery to create open sinus cavities and improve ostiomeatal complex drainage). Many patients relapse despite medical and surgical treatment. 3 current medications are used to target type 2 inflammation to improve […]