AR201 is currently being developed by Aimmune Therapeutics for the treatment of egg allergy. If Aimmune sounds familiar to you, it is because they will be releasing the first treatment of peanut allergy by the end of 2019, AR101. AR101 a Potential Peanut Allergy Cure Aimmune expects to initiate a Phase 2 clinical trial of […]
Am I Allergic to Penicillin?
Recent studies have shown that more than 90% of patients labeled as allergic to penicillin were found to be tolerant of penicillin. Current guidelines encourage routine penicillin allergy verification because of substantial clinical and economic consequences of a penicillin allergy label.However, penicillin testing can be prohibited by time, personnel and resource constraints. A recent study […]
Food Allergy and C-sections, what is the influence?
A recent study looked at the correlation of food allergy and birth conditions. Namely the association between C-sections, preterm birth, low birth weight, small for gestational age, large for gestational age and low Apgar scores and future food allergy. The prevalence of food allergy is increasing and there is an interest in environmental components, very […]
When multiple epinephrine doses are needed for food anaphylaxis
Multiple epinephrine dosages are sometimes need for anaphylaxis. Anaphylaxis is a severe, potentially fatal allergic reaction. Intramuscular epinephrine is the recommended treatment in the the setting of anaphylaxis and the current recommendation is for patients to carry 2 doses of self-injectable epinephrine. Previous studies have evaluated food-induced allergic reactions that require multiple epinephrine injections in […]
NBA Rookie Zhaire Smith’s Allergic Reaction
In reported news today, Zhaire Smith of the Philadelphia 76’ers will be out possibly the whole NBA 2018-2019 season due to complications from an allergic reaction. It was known that the rookie had a peanut allergy and food was individually prepared for him at the teams facility so he was not exposed to peanut. Apparently […]
Primatene Mist OTC gets FDA Approval
Primatene Mist OTC is making a comeback as it was recently FDA approved. Primatene Mist was taken off the market in the past because it contained CFC propellants that destroyed the ozone layer, we discussed this several years ago. Primatene Mist not likely to get FDA approval But the new version of Primatene Mist OTC […]
Alternaria mold is associated with Asthma
The importance of Alternaria mold exposure to allergic disease is underrecognized in urban communities compared to dust mites, cockroach and mouse exposure. Concentrations of Alternaria mold are higher in outdoor than in indoor air, however dampness, leaks can cause fungal penetration and growth indoors. Given the amount of time people spend indoors, indoor exposure may […]
Pectin Allergy, a potential hidden food allergen
Pectin allergy is not very common, but it can be a source of allergy for patients sensitive to cashew and pistachio. Food allergy is estimated to affect 6-8% of children in the United states and it is associated with a risk of anaphylaxis. Despite avoidance to culprit foods, hidden allergens can be a source of […]
Statins for Asthma, do they help?
Statins for asthma have been recently looked at as they have anti-inflammatory and immunomodulatory effects. Asthma is a respiratory syndrome defined by reversible airway obstruction and increased hyperreactivity of the airways. The estimated prevalence in some studies show asthma prevalence up to 13% worldwide. Statins are prescribed for elevated cholesterol and prevention of cardiovascular disease. […]
Are Two EpiPens Really Necessary?
Having two epipens has become more difficult for patients due to recent shortages, rising prices and manufacturing difficulties. Anaphylaxis is a life-threatening allergic reaction characterized by skin, respiratory and gastrointestinal allergy symptoms with a rapid onset. Anaphylaxis affects both adults and children and it can occur up to 2% of the population. Among pediatrics, the […]