There is no current cure for peanut allergy. Accidental exposures are common and can be severe. To assess children who had severe reactions during oral peanut challenges, scientists identified certain biomarkers that would help them see who would be at higher risk with accidental ingestion of 0.1 gram of peanut protein (about half a peanut […]
Chronic Hives work up not essential or cost effective
Chronic hives or chronic spontaneous urticaria or chronic idiopathic urticaria or chronic autoimmune urticaria is characterized by moving, itching wheals that occur with variable frequency for 6 weeks duration or more. Stepwise approach to Chronic Urticaria (Chronic Hives) It can occur in adults and pediatrics, but it is more common in adults. It is usually […]
Dr. Alan Khadavi for Wikihow
Dr. Alan Khadavi recently helped collaborate on several allergy topics with Wikihow that were of interest to its readers. Please click on the links below for detailed descriptions on topics co-authored by Dr. Khadavi pertaining to allergies. How to prevent hay fever How to manage grass allergies How to patch test the skin How […]
Covid with Xolair, Nucala, Cinqair, Fasenra or Dupixent for Asthma
As Covid-19 continues to spread around the world, there are concerns that patients with asthma will be at higher risk or poorer outcomes. There is also concern about whether asthma treatments could worsen the risk of disease or severity. Currently, asthma is not in the top 10 comorbidities associated with Covid-19 fatalities, obesity, diabetes and […]
Newborns born to Covid-19 Mothers
Humans are susceptible to SARS-CoV-2 and pregnant women and newborns are potential at-risk groups for COVID-19. Coronavirus infections in pregnant women can cause adverse consequences, such as spontaneous miscarriage, preterm delivery and intrauterine growth restriction and stillbirth. As of now, there is no evidence of mother to child vertical transmission of SARS-CoV-2, it is important […]
CVID and Covid-19, what are their outcomes?
SARS-CoV-2 has become the focus of scientific attention. The presentation of COVID-19 can range from lack of symptoms to severe respiratory distress and multiorgan failure requiring ICU admission and mechanical ventilation and eventual death. CVID (common variable immune deficiency) are characterized of having primary antibody deficiencies with defective antibody production (IgG). A study published in the […]
New Treatment for Hives being studied
The current only approved treatment for hives are antihistamines and Xolair (omalizumab). Omalizumab is approved for the treatment of chronic hives for those 12 years and older (it is approved for 6 years and older in asthma). New treatment for hives are on the horizon. Stepwise approach to Chronic Urticaria (Chronic Hives) Ligelizumab is a […]
Abrocitinib for Atopic Dermatitis by Pfizer
Abrocitinib is currently being developed by Pfizer for the treatment of atopic dermatitis (eczema). It is an investigational oral once-daily Janus kinase 1 (JAK1) inhibitor. The JAK/STAT pathway is an important factor in inflammation and itch in atopic dermatitis. There are multiple receptors and signaling cascades involved in eczema related inflammation and itch, one of these […]
Is Clarinex safe during Pregnancy?
Is Clarinex safe during pregnancy? Clarinex, generic name is desloratadine does not have safety data to use during pregnancy. Loratadine (Claritin) has been previously studied and found no risk of adverse fetal outcomes during pregnancy and is considered safe. Desloratadine is the main active metabolite of Loratadine. In a previous post we described the difference […]
Breztri new inhaler for COPD by AstraZeneca
Breztri is a new inhaler that will be approved for COPD. Breztri is a combination of 3 medications, budesonide/glycopyrronium/formoterol fumarate. Each of these medications have been used to treat COPD (chronic obstructive pulmonary disease), and used in combination, it has been shown to decrease the rate of moderate or severe exacerbations. We have spoken about […]