Los Angeles Allergist

Los Angeles Allergist

Alan Khadavi, MD, APC
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9001 Wilshire Blvd. Suite 204
Beverly Hills, CA 90211
Phone: 310-282-8822

16260 Ventura Blvd., Suite 140
Encino, CA 91436
Phone: 818-528-7776

December 5, 2021 by Alan Khadavi

Gefapixant for Chronic Cough by Merck

gefapixant

Gefapixant is a selective P2X3 receptor antagonist being currently developed by Merck for chronic unexplained cough. Chronic cough is a significant issue for many patients. It is estimated that between 5-10% of the population has it at one time. Many patients with chronic cough have underlying allergies that cause post nasal drip, asthma or acid […]

Filed Under: Allergy Medicine, Blog

November 29, 2021 by Alan Khadavi

JAK inhibitors for asthma, a new treatment option

JAK inhibitors for asthma

JAK inhibitors for asthma are currently being studied. Asthma is an inflammatory disease of the airways characterized by intermittent episodes of wheezing, chest tightness and cough. Many of the inflammatory pathways implicated in asthma involve factors that activate the Janus Kinase (JAK). The discovery of the Janus kinases activator of transcription (STAT) signaling pathway was […]

Filed Under: Asthma, Blog

November 1, 2021 by Alan Khadavi

PEG Allergy and Vaccine Allergy

peg allergy

PEG allergy has become an important topic since the COVID-19 vaccine rollout. There are 2 messenger RNA vaccines that have been approved in multiple countries around the world. Pfizer Covid Vaccine and Allergy Moderna Covid Vaccine and Allergy There are 3 adenovirus vector vaccines as well. Johnson and Johnson Covid Vaccine and Allergy Since the vaccine […]

Filed Under: Blog, Headlines, Medications

October 25, 2021 by Alan Khadavi

Should you taken an antihistamine before allergy shots?

antihistamines before allergy shots

An antihistamine before allergy shots may help prevent adverse reactions. Allergy shots is the only potential disease modifying treatment for allergic diseases (oral immunotherapy is also as well). The typical process of allergy immunotherapy involves regular administration of increasing doses of sensitizing allergy to a targeted maintenance dose. Allergy immunotherapy can come in different routes, […]

Filed Under: Allergy Medicine, Blog

September 25, 2021 by Alan Khadavi

Opzelura (ruxolitinib) for Eczema

Opzelura

Opzelura (ruxolitinib) has been FDA approved for eczema. Opzelura is a topical JAK inhibitor, and its indicated for short term use in patients 12 and up who have mild to moderate atopic dermatitis. It is the first topical janus kinase inhibitor approved in the United States. Currently for atopic dermatitis topical treatment, the mainstay of […]

Filed Under: atopic dermatitis, Blog, Medications

September 25, 2021 by Alan Khadavi

Allergy and Eustachian Tube Dysfunction

allergy and eustachian tube

Is there a link between allergy and eustachian tube dysfunction?  Symptoms of eustachian tube dysfunction are: fullness in the ears feeling like your ears are “plugged” changes to your hearing ringing in the ear clicking or popping sounds ticklish feelings in the ears pain The Eustachian tube is a small passageway that connects your throat […]

Filed Under: Blog, Headlines

September 25, 2021 by Alan Khadavi

Upadacitinib for Atopic Dermatitis (Eczema)

upadacitinib

Upadacitinib is an oral JAK1 inhibitor being developed for patients with severe atopic dermatitis. Multiple phase 2 randomized placebo controlled studies have examined the efficacy of upadacitinib in adults and adolescent patients with moderate to severe atopic dermatitis. Published in The Lancet, 2 replicate 16-week trials showed that monotherapy with upadacitinib improved symptom and disease severity compared […]

Filed Under: atopic dermatitis, Blog

September 18, 2021 by Alan Khadavi

Tomato Allergy can come in many flavors

tomato allergy

Tomato allergy is not commonly reported, but it can cause adverse reactions.  Hypersensitivity reactions to other fruits are commonly reported, particularly apples, stone fruits and bananas. Tomato (Solanum lycopersicum) is derived from two wild ancestor species, Solanum pimpinellifolium and Solanum cerasiforme. Tomato flavor is a balance of acid and sugar recognized by the tongue and […]

Filed Under: Blog, Food allergy

August 31, 2021 by Alan Khadavi

Can you outgrow fish allergy?

outgrow fish allergy

The data of whether someone can outgrow fish allergy is scarce. Fish allergy is one of the most common causes of food allergy, especially in children and young adults, with rates from 0.1 to 0.5%. The major fish allergen identified is beta-parvalbumin, it is resistant to heat and digestion. Many patients with an allergic reaction […]

Filed Under: Blog, Food allergy

August 29, 2021 by Alan Khadavi

Eczema and Dementia Risk

asivatrep cream

Past studies have suggested that there is a link between eczema and dementia. Patients with dementia have a higher prevalence of eczema than those without. According the the World Health Organization, eczema (atopic dermatitis) is 15th among all nonfatal diseases and is the largest disease burden among all skin diseases.  Eczema peaks in early childhood, […]

Filed Under: atopic dermatitis, Blog

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alan-khadavi
Dr. Alan Khadavi
Allergy & Asthma Specialist

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