Nucala vs. Fasenra for Severe Asthma: Which Biologic Is Better? For patients with severe eosinophilic asthma, biologic medications can dramatically reduce asthma attacks and the need for oral steroids. Two commonly used options are Nucala (mepolizumab) and Fasenra (benralizumab). Both target eosinophilic inflammation, but they work in slightly different ways. What Is Eosinophilic Asthma? Eosinophils […]
Rademikibart: A New Biologic in Development for Asthma
Asthma treatment has advanced significantly over the past decade, especially with the introduction of biologics—specialized therapies that target specific pathways in the immune system. Now, a new investigational drug called Rademikibart (formerly known as CM310) is showing promise as the next potential biologic treatment for patients with moderate-to-severe asthma. What Is Rademikibart? Rademikibart is a […]
New Asthma Treatments
New asthma treatments are on the horizon. Asthma remains a major public health concern, affecting millions of individuals worldwide. Traditional treatments have long relied on inhaled corticosteroids and bronchodilators to control symptoms and reduce exacerbations. However, recent advancements in asthma management have introduced novel therapies that target the underlying inflammatory mechanisms of the disease. The […]
Depemokimab (Exdensur) a twice yearly injection for severe asthma
Severe eosinophilic asthma (SEA) is a challenging subtype of asthma characterized by elevated eosinophil levels and frequent exacerbations despite standard therapies. Depemokimab, a novel ultra long-acting anti-IL-5 monoclonal antibody, has emerged as a promising treatment option. This review examines the efficacy, safety, and potential role of twice-yearly depemokimab injections in managing SEA, based on recent […]
Cinqair vs. Nucala vs. Dupixent for Asthma
A direct comparison study of Cinqair vs. Nucala vs. Dupixent for Asthma. Which asthma biologic medication works best? There are many new asthma biological drugs on the market and for the allergist, it can be difficult to choose which one is right for the patient. Head to head studies are not commonly done by the […]
Dr. Alan Khadavi discusses Asthma with Health Central
Dr. Alan Khadavi recently contributed to the medical articles on the following asthma topics with Health Central What’s the Difference Between Advair and Flovent for Asthma? Pulmicort vs. Symbicort for Asthma: What’s the Difference? Ventolin vs. Atrovent for Asthma: How Are They Different? Can You Take Advair and Spiriva Together for Asthma?
A comparison of asthma biologic therapies
A comparison of asthma biologic therapies have not been directly done. A recent study published in the [Annals of of Allergy, Asthma and Immunology 130 (2023) pg 595-606], sought to do that. They compared Dupixent, Tezspire, Xolair, Cinqair, Nucala, Fevipiprant, and Fasenra. 64 trials were included, consisting of more than 25,000 patients. The optimal biologic […]
Xolair vs. Nucala vs. Dupixent in Asthma, which is the best?
Xolair vs. Nucala vs. Dupixent Multiple biologics are approved for the the treatment of severe asthma. However, there are no head to head studies comparing them. Many patients can potentially be approved for multiple of them and it can be difficult to choose which would work best. So the optimal choice may be uncertain. All […]
Does an Air Purifier help Asthma?
Does an Air Purifier help asthma or allergies, is a common question asked among allergy specialists. There is evidence that indoor air pollution is associated with poor asthma outcomes, including hospitalizations and asthma medication use, poorer lung function and asthma-related mortality. So reducing indoor air pollution is likely important for improving outcomes in people with […]
Tezspire vs. Nucala vs. Fasenra vs. Dupixent for Eosinophilic Asthma, a comparison
With the influx of new biological medications for asthma, the question is which one is the best to use in comparing Tezspire, Nucala, Fasenra and Dupixent? In many individuals, asthma remains uncontrolled despite the use of inhaled steroids, the use of new biological injections can improve symptoms greatly. There are no head to head trials […]