A recent study looked at the correlation of food allergy and birth conditions. Namely the association between C-sections, preterm birth, low birth weight, small for gestational age, large for gestational age and low Apgar scores and future food allergy. The prevalence of food allergy is increasing and there is an interest in environmental components, very […]
Common Eczema Triggers
Eczema is a dry, red, itchy skin condition. It affects approximately 10% of the population in the United States, it is most commonly found in children, but it can affect adults as well. Eczema or atopic dermatitis is often triggered by food or environmental allergens. Contact dermatitis is a reaction to allergens and irritants such […]
PR022 for Atopic Dermatitis (Eczema)
PR022 is a new topical gel being studied for the treatment of atopic dermatitis. It is entering Phase 2 trials and it is being manufactured by Realm Therapeutics. Data is supposed to come out in the 3rd quarter of 2018. PR022 consists of hypochlorous acid (HOCL). HOCL is an ideal wound care agent with powerful […]
Food Diversity and Allergic Disease
Food diversity has been a hot topic in allergy since several clinical trials in high-risk children reported that early introduction of highly allergenic foods, especially peanut and egg, prevents food allergy later in life. This opened up the debate about changing recommendations about the timing of solid food introduction and the length of breast feeding […]
Do Bleach Baths Improve Eczema?
Eczema or atopic dermatitis is a chronic, relapsing inflammatory skin disorder affecting 15%-20% of children and 1%-10% of adults in the U.S. and worldwide. Deficiencies in the skin barrier and immune system dysfunction contribute to eczema, resulting in dryness and itching. Eczema patients are predisposed to to skin infections and patients have a high concentration […]
Criteria for Dupixent (dupilumab) for Eczema
There is no set criteria for dupixent (dupilumab), but there are guidelines in place that Regeneron and Sanofi recommend to get patients enrolled through their insurance companies. Every insurance company has their own criteria, but under Regeneron and Sanofi’s, Dupixent My Way, they set out guidelines which would help get approval easier for Dupixent. Being a very […]
How to Prevent Eczema in Children
In order to prevent eczema children, we first need to discuss atopic dermatitis (eczema) first. Atopic dermatitis affects 17-24% of the pediatric population and 4-7% of adults. It develops in the first 6 months in about half the children and by 5 years of age in 85% of the cases. Only about half of affected […]
Nemolizumab for Itching and Atopic Dermatitis
Nemolizumab is a new medication being currently developed by Chugai Pharmaceutical Company. It will be licensed and developed by Galderma Pharma who picked up the rights to it. With the recent ground breaking FDA approval of Dupixent (dupilumab) for eczema, this will help many patients suffering itchy, inflamed dry skin. As with all new biological […]
ZPL389, New Oral Eczema Drug in the Pipeline
ZPL389 is a new once-daily oral H4 receptor antagonist that is currently being studied for the treatment of atopic dermatitis, commonly referred as eczema. Novartis recently purchased the rights to this medication from Ziarco, a private company focused on the development of treatments in dermatology. There currently is no specific oral medication used for the […]
Eucrisa (crisaborole) New Eczema Medication gets FDA Approval
Eucrisa (crisaborole) recently won FDA approval for eczema (atopic dermatitis). This would be the first non-steroidal skin therapy for eczema in 15 years, since Elidel and Protopic were approved. Pfizer recently bought the rights to Eucrisa (crisaborole) back in May when it acquired its developer, Anacor, for 5.2 billion dollars. There were 2 trials, consisting […]