Los Angeles Allergist

Los Angeles Allergist

Alan Khadavi, MD, APC
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9001 Wilshire Blvd. Suite 204
Beverly Hills, CA 90211
Phone: 310-282-8822

16260 Ventura Blvd., Suite 140
Encino, CA 91436
Phone: 818-528-7776

April 19, 2022 by Alan Khadavi

Fasenra for Nasal Polyps, a new treatment option

fasenra for nasal polyps

Fasenra for nasal polyps is currently being studied as a future therapeutic option. Chronic sinusitis with nasal polyps is an inflammatory condition associated with symptoms that may be severe, including rhinorrhea, nasal blockage and congestion, loss of smell, facial pressure/pain. Nasal sprays have shown limited help and surgery only helps temporarily as many of them […]

Filed Under: biologics, Blog

March 8, 2022 by Alan Khadavi

Itepekimab in Asthma and COPD

airsupra

Itepekimab is an anti-Il-33 monoclonal. Il-33 is an epithelium-derived cytokine that promotes Th2 immune responses in response to cellular damage with roles in asthma and COPD (Chronic Obstructive Pulmonary Disease). Two randomized controlled clinical trials were performed assessing the efficacy of Itepekimab in asthma and COPD. After identifying the asthma associated variants in the genes […]

Filed Under: Asthma, biologics, Blog

February 12, 2022 by Alan Khadavi

Xolair, Dupixent or Nucala for Nasal Polyps?

dupixent xolair nucala nasal polyps

Xolair, Dupixent and Nucala all have the indication to treat chronic rhinosinusitis with nasal polyps. Conventional treatment involves nasal surgery (debulking polypectomy and sinus surgery to create open sinus cavities and improve ostiomeatal complex drainage). Many patients relapse despite medical and surgical treatment. 3 current medications are used to target type 2 inflammation to improve […]

Filed Under: biologics, Blog

January 6, 2022 by Alan Khadavi

New Eosinophilic Esophagitis Treatments

dupixent for eoe

New Eosinophilic esophagitis treatments are currently being studied. As of today, there are no eosinophilic esophagitis treatments that are FDA approved. On the horizon is Eohilia Budesonide Oral Suspension for Eosinophilic Esophagitis. Plus there are many other ways that EoE can be treated, but there are no official medications yet. Here we will discuss new eosinophilic […]

Filed Under: Allergy Medicine, biologics, Blog

July 9, 2021 by Alan Khadavi

Nasal Polyps Treatment; Past, Present and Future

best nasal polyps treatment

Nasal polyps treatment have shown great advances recently, and many more treatments are on the horizon. Nasal polyps are used to describe chronic rhinosinusitis associated with the formation of nasal polyps.  Nasal polyps affect 2-4% of adults globally. About 50% of patients have existing allergies. Nasal polyps are semitranslucent, pale grey, grape-like, benign inflammatory lesions […]

Filed Under: Allergy Medicine, biologics, Blog, Medications, Uncategorized

May 11, 2021 by Alan Khadavi

Abrocitinib vs. Dupilumab for Atopic Dermatitis

Can allergy shots help eczema?

Abrocitinib vs. Dupilumab will be an important question for many prescribing doctors with the expected FDA approval of abrocitinib soon. We have extensively discussed atopic dermatitis (eczema) in the past. For many years only topical therapies were available for this condition. Topical steroids are the mainstays of treatment, and after many years newer topical therapies […]

Filed Under: atopic dermatitis, biologics, Blog

October 29, 2020 by Alan Khadavi

Xolair for Allergic Rhinitis-A recent study

xolair for allergic rhinitis

Xolair for allergic rhinitis may become a future treatment option for patients. Currently Xolair which is an anti-IgE antibody is indicated for moderate to severe persistent asthma and chronic idiopathic urticaria. But the mechanism of action lends itself to treating allergic rhinitis. Allergic rhinitis is one of the most common and increasing diseases worldwide, affecting […]

Filed Under: biologics, Blog

September 21, 2020 by Alan Khadavi

Xolair for Nasal Polyps

xolair for nasal polyps

The treatment of Xolair for nasal polpys is currently being investigated. Chronic sinusitis with nasal polyps is common and is estimated to affect up to 15% of the population. It is associated with adult onset asthma. Many patients have uncontrolled symptoms despite use of nasal steroids. Even after surgery up to 80% of patients can […]

Filed Under: biologics, Blog

August 11, 2020 by Alan Khadavi

Covid with Xolair, Nucala, Cinqair, Fasenra or Dupixent for Asthma

JAK inhibitors for asthma

As Covid-19 continues to spread around the world, there are concerns that patients with asthma will be at higher risk or poorer outcomes. There is also concern about whether asthma treatments could worsen the risk of disease or severity. Currently, asthma is not in the top 10 comorbidities associated with Covid-19 fatalities, obesity, diabetes and […]

Filed Under: biologics, Blog

July 2, 2020 by Alan Khadavi

New Treatment for Hives being studied

Can allergy shots help eczema?

The current only approved treatment for hives are antihistamines and Xolair (omalizumab). Omalizumab is approved for the treatment of chronic hives for those 12 years and older (it is approved for 6 years and older in asthma). New treatment for hives are on the horizon. Stepwise approach to Chronic Urticaria (Chronic Hives) Ligelizumab is a […]

Filed Under: biologics, Blog, hives

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