Los Angeles Allergist

Los Angeles Allergist

Alan Khadavi, MD, APC
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9001 Wilshire Blvd. Suite 204
Beverly Hills, CA 90211
Phone: 310-282-8822

16260 Ventura Blvd., Suite 140
Encino, CA 91436
Phone: 818-528-7776

August 27, 2020 by Alan Khadavi

Chronic Hives work up not essential or cost effective

chronic spontaneous urticaria

Chronic hives or chronic spontaneous urticaria or chronic idiopathic urticaria or chronic autoimmune urticaria is characterized by moving, itching wheals that occur with variable frequency for 6 weeks duration or more. Stepwise approach to Chronic Urticaria (Chronic Hives) It can occur in adults and pediatrics, but it is more common in adults. It is usually […]

Filed Under: Blog, hives, Urticaria

July 2, 2020 by Alan Khadavi

New Treatment for Hives being studied

abrocitinib vs. dupilumab

The current only approved treatment for hives are antihistamines and Xolair (omalizumab). Omalizumab is approved for the treatment of chronic hives for those 12 years and older (it is approved for 6 years and older in asthma). New treatment for hives are on the horizon. Stepwise approach to Chronic Urticaria (Chronic Hives) Ligelizumab is a […]

Filed Under: biologics, Blog, hives

May 21, 2020 by Alan Khadavi

High dose Xolair for chronic hives

chronic hives

High dose Xolair may be a treatment option for patients with chronic hives who fail the standard treatment dose of 300mg monthly. Xolair (omalizumab) is a monoclonal anti-IgE antibody for patients who have chronic spontaneous urticaria who fail the 4 fold standard dosing of antihistamines. Stepwise approach to Chronic Urticaria (Chronic Hives) A recent study […]

Filed Under: Blog, hives

March 24, 2020 by Alan Khadavi

Can you taper your Xolair dosage for hives?

xolair for idiopathic angioedema

Chronic spontaneous urticaria involves recurrent episodes of hives with or without swelling for 6 weeks or longer from unknown causes.  Although chronic hives tends to be self-limited in most patients, it affects quality of life.  Most studies show that it affects 0.5% to 1% of the general population.  The trigger is unknown and treatment includes […]

Filed Under: biologics, Blog, hives

June 13, 2019 by Alan Khadavi

Dupixent for Hives

chronic spontaneous urticaria

Dupixent for hives is novel treatment option for patients with difficult to treatment chronic spontaneous urticaria.  Chronic hives is a common condition marked by episodes of elevated, itching, red wheals persisting for more than 6 weeks without a specific known cause.  It is estimated that chronic hives affects about 1% of the population. The mechanism […]

Filed Under: biologics, Blog, hives, Urticaria

April 25, 2019 by Alan Khadavi

Cold Hives (urticaria): A review

cold hives

Cold hives (or urticaria), is a subtype of physical hives that is characterized by the development of hives and swelling in response to cold exposure and rewarming of the skin.  It is related to the histamine release of mast cells.  Several studies have shown that it is related to IgE and an unknown skin autoallergen […]

Filed Under: angioedema, Blog, hives, Urticaria

August 22, 2018 by Alan Khadavi

Solar Urticaria (Sun Hives)

solar urticaria

Solar urticaria, is a type of skin response after exposure to the sun.  There is an abrupt onset of redness, swelling and itching in light exposed areas.  The light waves that trigger solar urticaria are usually within the range of 400 to 700 nm (visible light) and 320 to 400 nm (UV A).  Patients often […]

Filed Under: biologics, Blog, hives

September 29, 2017 by Alan Khadavi

Systemic Complaints in Chronic Urticaria (hives)

chronic spontaneous urticaria

Most people who have chronic urticaria (hives) complain of severe itching.  Chronic urticaria or chronic hives is associated with welts with or without swelling that generally resolve within 24 hours.  It is considered chronic if it lasts 6 weeks or longer.  Another term used is chronic spontaneous urticaria or chronic idiopathic urticaria.  An estimated 80-90% […]

Filed Under: Blog, hives, Uncategorized

September 26, 2017 by Alan Khadavi

Dermographism treated with Xolair

Opzelura

Dermographism is the most common form of physical urticaria with a prevalence of up to 5%.  Dermographism is characterized by itchy wheals that occur in response to friction, i.e. after rubbing or scratching of the skin and it usually lasts 1 to 2 hours.  Dermographism usually lasts for years and it impacts quality of life. […]

Filed Under: Blog, hives

August 3, 2017 by Alan Khadavi

Altered Gut Microbes in Chronic Hives

Gut Microbes in Chronic Hives

An altered gut microbe composition has recently been linked to some types of allergies.  In chronic urticaria (hives), hives are present continuously or intermittently for at least 6 weeks. Stepwise approach to Chronic Urticaria (Chronic Hives) The precise cause of chronic hives is unknown and the major treatment is symptomatic control.  Chronic hives is an […]

Filed Under: Blog, hives

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