Los Angeles Allergist

Los Angeles Allergist

Alan Khadavi, MD, APC
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9001 Wilshire Blvd. Suite 204
Beverly Hills, CA 90211
Phone: 310-282-8822

16260 Ventura Blvd., Suite 140
Encino, CA 91436
Phone: 818-528-7776

April 19, 2022 by Alan Khadavi

Asivatrep a new topical treatment for Eczema

asivatrep cream

Asivatrep is a new potential treatment for eczema (atopic dermatitis). Atopic dermatitis is a chronic inflammatory itchy skin disease that affects up to 25% of children and 10% of adults. The cause is complex and multifactorial. Currently there are few classes of topical medications to treat it. Steroids Calcineurin inhibitors (Elidel, Protopic) Phosphodiesterase 4 inhibitors Eucrisa […]

Filed Under: atopic dermatitis, Blog, Medications

November 1, 2021 by Alan Khadavi

PEG Allergy and Vaccine Allergy

peg allergy

PEG allergy has become an important topic since the COVID-19 vaccine rollout. There are 2 messenger RNA vaccines that have been approved in multiple countries around the world. Pfizer Covid Vaccine and Allergy Moderna Covid Vaccine and Allergy There are 3 adenovirus vector vaccines as well. Johnson and Johnson Covid Vaccine and Allergy Since the vaccine […]

Filed Under: Blog, Headlines, Medications

September 25, 2021 by Alan Khadavi

Opzelura (ruxolitinib) for Eczema

Opzelura

Opzelura (ruxolitinib) has been FDA approved for eczema. Opzelura is a topical JAK inhibitor, and its indicated for short term use in patients 12 and up who have mild to moderate atopic dermatitis. It is the first topical janus kinase inhibitor approved in the United States. Currently for atopic dermatitis topical treatment, the mainstay of […]

Filed Under: atopic dermatitis, Blog, Medications

July 9, 2021 by Alan Khadavi

Nasal Polyps Treatment; Past, Present and Future

best nasal polyps treatment

Nasal polyps treatment have shown great advances recently, and many more treatments are on the horizon. Nasal polyps are used to describe chronic rhinosinusitis associated with the formation of nasal polyps.  Nasal polyps affect 2-4% of adults globally. About 50% of patients have existing allergies. Nasal polyps are semitranslucent, pale grey, grape-like, benign inflammatory lesions […]

Filed Under: Allergy Medicine, biologics, Blog, Medications, Uncategorized

April 27, 2021 by Alan Khadavi

Baricitinib for Atopic Dermatitis (Eczema)

asivatrep cream

Baricitinib is currently being studied for the treatment of atopic dermatitis. Baricitinib is part of the family of oral Janus kinase inhibitors that are an emerging modality in the treatment of chronic allergic inflammatory disorders due to their ability to inhibit signaling of multiple pathways of cytokines. We discussed in another blog post, Abrocitinib which is […]

Filed Under: atopic dermatitis, Blog, Medications

April 7, 2021 by Alan Khadavi

New Urticaria Treatment Options being studied

new urticaria

New urticaria treatment options are currently being studied for patients with chronic spontaneous urticaria. Currently the only approved biologic medication approved for this condition is Xolair. Several medications are also being used off label and novel biologics are currently in development. Here we discuss them: Dupilumab– In preclinical studies, dupilumab (Dupixent) blocked several functions of […]

Filed Under: Blog, Medications

February 5, 2021 by Alan Khadavi

Capsaicin for Nonallergic Rhinitis

capsaicin nasal

Capsaicin nasal spray may be an effective treatment for patients who have nonallergic rhinitis. A significant proportion (25-30%) of patients suffering from rhinitis have nasal symptoms without an infection or allergies, this is referred to nonallergic rhinitis. Up to 50% of these patients have idiopathic rhinitis after excluding work, elderly, gustatory, hormonal and drug induced […]

Filed Under: Allergy Medicine, Blog, Medications

January 11, 2021 by Alan Khadavi

Allegra during Pregnancy, is it safe?

allegra during pregnancy

Allegra during pregnancy, is it safe to use? Antihistamines are commonly prescribed to pregnant women. Cetirizine (Zyrtec) and loratadine (Claritin) are considered safe to use during pregnancy, but there are few data on the safety of Allegra (fexofenadine) for the fetus. A study published in the JAMA Pediatrics titled “Association between fexofenadine use during pregnancy […]

Filed Under: Blog, Medications

December 1, 2020 by Alan Khadavi

Indacaterol for severe asthma

indacaterol

Indacaterol is an ultra long acting beta agonist that is currently only FDA approved to treat COPD.  Indacaterol containing inhalers have shown promise in 2 recent phase 3 trials in patients with severe uncontrolled asthma. For both trials, the endpoint was measured on spirometry and it studied the FEV1 after 26 weeks of treatment. In […]

Filed Under: Asthma, Blog, Medications

June 30, 2020 by Alan Khadavi

Cibinqo Abrocitinib for Atopic Dermatitis by Pfizer

abrocitinib

Cibinqo Abrocitinib is currently being developed by Pfizer for the treatment of atopic dermatitis (eczema). It is an investigational oral once-daily Janus kinase 1 (JAK1) inhibitor. The JAK/STAT pathway is an important factor in inflammation and itch in atopic dermatitis.  There are multiple receptors and signaling cascades involved in eczema related inflammation and itch, one […]

Filed Under: biologics, Blog, Medications

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