Los Angeles Allergist

Los Angeles Allergist

Alan Khadavi, MD, APC
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9001 Wilshire Blvd. Suite 204
Beverly Hills, CA 90211
Phone: 310-282-8822

16260 Ventura Blvd., Suite 140
Encino, CA 91436
Phone: 818-528-7776

November 3, 2020 by Alan Khadavi

New treatments for chronic hives

New treatments for chronic hives

New treatments for chronic hives are currently being studied. Chronic urticaria or hives is defined as having urticaria for more than 6 weeks duration. Chronic hives have been called chronic idiopathic urticaria, chronic autoimmune urticaria or chronic spontaneous urticaria. There is also chronic inducible urticaria which can be brought on by cold, delayed pressure, solar, […]

Filed Under: Blog, Urticaria

August 27, 2020 by Alan Khadavi

Chronic Hives work up not essential or cost effective

chronic spontaneous urticaria

Chronic hives or chronic spontaneous urticaria or chronic idiopathic urticaria or chronic autoimmune urticaria is characterized by moving, itching wheals that occur with variable frequency for 6 weeks duration or more. Stepwise approach to Chronic Urticaria (Chronic Hives) It can occur in adults and pediatrics, but it is more common in adults. It is usually […]

Filed Under: Blog, hives, Urticaria

June 13, 2019 by Alan Khadavi

Dupixent for Hives

chronic spontaneous urticaria

Dupixent for hives is novel treatment option for patients with difficult to treatment chronic spontaneous urticaria.  Chronic hives is a common condition marked by episodes of elevated, itching, red wheals persisting for more than 6 weeks without a specific known cause.  It is estimated that chronic hives affects about 1% of the population. The mechanism […]

Filed Under: biologics, Blog, hives, Urticaria

May 2, 2019 by Alan Khadavi

Mast Cell Activation Syndrome (MCAS): Fact & Fiction

mast cell activation syndrome

Mast cell activation syndrome (MCAS) is a rare condition defined by a severe systemic reaction to mast cell derived mediators.  Mast cells are effector cells of the immune system.  These cells produce a variety of proinflammatory mediators and participate in a number of different pathological conditions.  In patients the risk of developing severe anaphylactic (hypersensitivity) events […]

Filed Under: Blog, Headlines, Urticaria

April 25, 2019 by Alan Khadavi

Cold Hives (urticaria): A review

cold hives

Cold hives (or urticaria), is a subtype of physical hives that is characterized by the development of hives and swelling in response to cold exposure and rewarming of the skin.  It is related to the histamine release of mast cells.  Several studies have shown that it is related to IgE and an unknown skin autoallergen […]

Filed Under: angioedema, Blog, hives, Urticaria

December 28, 2017 by Alan Khadavi

Severe Hives Treatment (Xolair and Cyclosporine)

severe hives

Severe hives or chronic spontaneous urticaria is classified as hives with or without swelling that occurs for 6 weeks or more with an unknown cause.  The prevalence of chronic hives (also known as chronic idiopathic urticaria) is approximately 0.5% to 5% of the population.  Chronic hives may be active for 1-5 years at a time, […]

Filed Under: Blog, Urticaria

January 25, 2017 by Alan Khadavi

Alternative Agents for Refractory Chronic Urticaria Patients

ruxolitinib

Chronic urticaria is defined for a period of at least 6 weeks with hives.  Patients with chronic urticaria who fail high-dose antihistamines should be referred to an allergy specialist to help manage their condition.  We have previously spoke about the stepwise approach to chronic idiopathic/spontaneous urticaria. Stepwise approach to Chronic Urticaria (Chronic Hives) Patients with […]

Filed Under: Blog, hives, Urticaria

December 1, 2016 by Alan Khadavi

Omalizumab (Xolair) for treating Angioedema and Chronic Hives

xolair for nasal polyps

Omalizumab (Xolair) is being used to treat chronic hives (urticaria).  Chronic idiopathic/spontaneous urticaria (CIU/CSU) is characterized by the spontaneous appearance of hives, angioedema or both that recur without specific external stimuli for at least 6 weeks.  Angioedema, which is the acute deeper swelling of the lower skin or subcutaneous tissue has been reported to occur […]

Filed Under: Allergy Medicine, angioedema, Blog, Urticaria

October 25, 2016 by Alan Khadavi

Ligelizumab (QGE031) vs. Omalizumab (Xolair)

Ligelizumab (QGE031)

Ligelizumab (QGE031) is currently being developed by Novartis for the treatment of allergic diseases mainly asthma and chronic spontaneous urticaria.  Allergic diseases are dependent on the development of increased IgE levels.  Allergen-specific IgE plays a role in the inflammatory cascade of allergic responses.  Allergic individuals with elevated IgE levels have increased allergic mediators (e.g. histamine, […]

Filed Under: Allergy Medicine, Asthma, Blog, Urticaria

March 31, 2016 by Alan Khadavi

Sun Allergy (Solar Urticaria) Treatment

sun allergy

Sun allergy, also known as solar urticaria, is an uncommon, chronic and disabling form of physical urticaria (hives).  Wheals accompanied by itching or burning sensation appear after a few minutes on sun-exposed skin, disappearing after 1 to 2 hours.  In severe cases if the sun exposure is intense can lead to systemic symptoms or even […]

Filed Under: Blog, Urticaria

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