Roflumilast and Tapinarof are 2 emerging topical therapies that have completed or have ongoing phase 3 clinical trials, with the possibility of approval in 2022. Roflumilast is a more potent PDE4 inhibitor than crisaborloe (Eucrisa) with fewer local reactions. Tapinarof, the first therapeutic arylhydocarbon modulating agent for which the only associated local effect is noninfectious […]
Mango Allergy can come in many flavors
Mango allergy is not commonly reported, but it can cause adverse reactions. Hypersensitivity reactions to other fruits are commonly reported, particularly apples, stone fruits and bananas. The fruit mango (Mangifera indica) belongs to the family Anacardiacae and is often, regarded as the ‘king of fruits’. Mangoes are delicious simply peeled and eaten plain. They are also good […]
Nasal Polyps Treatment; Past, Present and Future
Nasal polyps treatment have shown great advances recently, and many more treatments are on the horizon. Nasal polyps are used to describe chronic rhinosinusitis associated with the formation of nasal polyps. Nasal polyps affect 2-4% of adults globally. About 50% of patients have existing allergies. Nasal polyps are semitranslucent, pale grey, grape-like, benign inflammatory lesions […]
Ara h 2 is the most important peanut allergen
Peanut allergy is a prominent IgE-mediated food allergy that can cause anaphylaxis and it is increasing in prevalence. Peanut allergy appears to be particularly persistent. Detection of allergen specific IgE supports the diagnosis of peanut allergy. Peanut Component Testing, can help diagnose specific peanut allergy. There are over 13 allergenic components identified in peanuts. The […]
AR201 a treatment for Egg Allergy by Aimmune
AR201 is currently being developed by Aimmune Therapeutics for the treatment of egg allergy. If Aimmune sounds familiar to you, it is because they will be releasing the first treatment of peanut allergy by the end of 2019, AR101. AR101 a Potential Peanut Allergy Cure Aimmune expects to initiate a Phase 2 clinical trial of […]
Am I Allergic to Penicillin?
Recent studies have shown that more than 90% of patients labeled as allergic to penicillin were found to be tolerant of penicillin. Current guidelines encourage routine penicillin allergy verification because of substantial clinical and economic consequences of a penicillin allergy label.However, penicillin testing can be prohibited by time, personnel and resource constraints. A recent study […]
Food Allergy and C-sections, what is the influence?
A recent study looked at the correlation of food allergy and birth conditions. Namely the association between C-sections, preterm birth, low birth weight, small for gestational age, large for gestational age and low Apgar scores and future food allergy. The prevalence of food allergy is increasing and there is an interest in environmental components, very […]
Systemic Complaints in Chronic Urticaria (hives)
Most people who have chronic urticaria (hives) complain of severe itching. Chronic urticaria or chronic hives is associated with welts with or without swelling that generally resolve within 24 hours. It is considered chronic if it lasts 6 weeks or longer. Another term used is chronic spontaneous urticaria or chronic idiopathic urticaria. An estimated 80-90% […]
New Peanut Guidelines
New peanut guidelines have been officially introduced by the National Institute of Allergy and Infectious Diseases in response to the earlier studies we have discussed from the LEAP trials. Peanut Allergy Prevention Peanut allergy is a growing public health problem. In the United States, peanut allergy prevalence is approximately 2% among children. Peanut allergy is […]